Version 5.4
Mus musculus Gene: Uaca
Summary
InnateDB Gene IDBG-173915.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Uaca
Gene Name uveal autoantigen with coiled-coil domains and ankyrin repeats
Synonyms 2700059D02Rik; nucling
Species Mus musculus
Ensembl Gene ENSMUSG00000034485
Encoded Proteins
IDBP-173917
uveal autoantigen with coiled-coil domains and ankyrin repeats
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000137831:
Gene Information
Type Protein coding
Genomic Location Chromosome 9:60794548-60880370
Strand Forward strand
Band B
Transcripts
ENSMUST00000050183 ENSMUSP00000062047
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage
GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress
GO:0009411 response to UV
GO:0042307 positive regulation of protein import into nucleus
GO:0042347 negative regulation of NF-kappaB import into nucleus
GO:0043065 positive regulation of apoptotic process
GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0050728 negative regulation of inflammatory response
Cellular Component
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0016020 membrane
GO:0043293 apoptosome
GO:0048471 perinuclear region of cytoplasm
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000137831
View Gene Order
ENSBTAG00000013982
Not yet available
Cross-References
SwissProt Q8CGB3
TrEMBL
UniProt Splice Variant
Entrez Gene 72565
UniGene Mm.68819
RefSeq NM_028283 XM_006511480 XM_006511481 XM_006511482 XM_006511483
OMIM
CCDS CCDS23259
HPRD
IMGT
MGI ID MGI:1919815
MGI Symbol Uaca
EMBL AB030647 AK087466 AK173203 BC042415
GenPept AAH42415 BAC39886 BAC78213 BAD32481
RNA Seq Atlas 72565

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca