Version 5.4
Mus musculus Gene: Pdcd11
Summary
InnateDB Gene IDBG-174050.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pdcd11
Gene Name programmed cell death 11
Synonyms 1110021I22Rik; ALG-4; mKIAA0185; Pdcd7
Species Mus musculus
Ensembl Gene ENSMUSG00000025047
Encoded Proteins
IDBP-174052
programmed cell death 11
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000148843:
PDCD11 is a NF-kappa-B (NFKB1; 164011)-binding protein that colocalizes with U3 RNA (MIM 180710) in the nucleolus and is required for rRNA maturation and generation of 18S rRNA (Sweet et al., 2003 [PubMed 14624448]; Sweet et al., 2008 [PubMed 17654514]).[supplied by OMIM, Oct 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:47090766-47131143
Strand Forward strand
Band C3
Transcripts
ENSMUST00000072141 ENSMUSP00000072008
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0006364 rRNA processing
GO:0006396 RNA processing
GO:0006397 mRNA processing
GO:0006915 apoptotic process
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005829 cytosol
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000148843
View Gene Order
ENSBTAG00000009715
Not yet available
Cross-References
SwissProt Q6NS46
TrEMBL Q3TUH3
UniProt Splice Variant
Entrez Gene 18572
UniGene Mm.41166 Mm.449236
RefSeq NM_011053
OMIM
CCDS CCDS29888
HPRD
IMGT
MGI ID MGI:1341788
MGI Symbol Pdcd11
EMBL AF055668 AF055669 AK003899 AK129080 AK141450 AK147950 AK160767 AK161803 BC038503 BC055276 BC070468
GenPept AAD20941 AAD20942 AAH38503 AAH55276 AAH70468 BAB23064 BAC97890 BAE24688 BAE28246 BAE35998 BAE36581
RNA Seq Atlas 18572

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca