Version 5.4
Mus musculus Gene: Agfg1
Summary
InnateDB Gene IDBG-174169.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Agfg1
Gene Name ArfGAP with FG repeats 1
Synonyms AU045498; C130049H11Rik; C85612; D730048C23Rik; Hrb; RAB; Rip
Species Mus musculus
Ensembl Gene ENSMUSG00000026159
Encoded Proteins
IDBP-174171
ArfGAP with FG repeats 1
IDBP-253867
ArfGAP with FG repeats 1
IDBP-790445
ArfGAP with FG repeats 1
IDBP-790446
ArfGAP with FG repeats 1
IDBP-790447
ArfGAP with FG repeats 1
IDBP-790449
ArfGAP with FG repeats 1
IDBP-790450
ArfGAP with FG repeats 1
IDBP-790451
ArfGAP with FG repeats 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000173744:
The protein encoded by this gene is related to nucleoporins, a class of proteins that mediate nucleocytoplasmic transport. The encoded protein binds the activation domain of the human immunodeficiency virus Rev protein when Rev is assembled onto its RNA target, and is required for the nuclear export of Rev-directed RNAs. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:82839483-82901182
Strand Forward strand
Band C5
Transcripts
ENSMUST00000063380 ENSMUSP00000070250
ENSMUST00000113444 ENSMUSP00000109071
ENSMUST00000189220 ENSMUSP00000140170
ENSMUST00000190052 ENSMUSP00000141157
ENSMUST00000187899 ENSMUSP00000139503
ENSMUST00000186302 ENSMUSP00000140785
ENSMUST00000190046 ENSMUSP00000140473
ENSMUST00000186043 ENSMUSP00000140678
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0008060 ARF GTPase activator activity
GO:0008270 zinc ion binding
Biological Process
GO:0001675 acrosome assembly
GO:0006810 transport
GO:0007275 multicellular organismal development
GO:0007289 spermatid nucleus differentiation
GO:0032312 regulation of ARF GTPase activity
GO:0043547 positive regulation of GTPase activity
GO:0045109 intermediate filament organization
Cellular Component
GO:0005634 nucleus
GO:0016023 cytoplasmic membrane-bounded vesicle
GO:0042995 cell projection
GO:0043025 neuronal cell body
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000173744
View Gene Order
ENSBTAG00000021323
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 15463
UniGene
RefSeq NM_010472 XM_006496433 XM_006496434 XM_006496435
OMIM
CCDS CCDS15100
HPRD
IMGT
MGI ID MGI:1333754
MGI Symbol Agfg1
EMBL
GenPept
RNA Seq Atlas 15463

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca