Version 5.4
Mus musculus Gene: Prps1
Summary
InnateDB Gene IDBG-174819.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Prps1
Gene Name phosphoribosyl pyrophosphate synthetase 1
Synonyms 2310010D17Rik; C76571; C76678; Prps-1; PRS-I
Species Mus musculus
Ensembl Gene ENSMUSG00000031432
Encoded Proteins
IDBP-174821
phosphoribosyl pyrophosphate synthetase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome X:140456613-140476140
Strand Forward strand
Band F1
Transcripts
ENSMUST00000033809 ENSMUSP00000033809
ENSMUST00000155235
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000287 magnesium ion binding
GO:0004749 ribose phosphate diphosphokinase activity
GO:0005524 ATP binding
GO:0016208 AMP binding
GO:0016301 kinase activity
GO:0019003 GDP binding
GO:0030246 carbohydrate binding
GO:0042803 protein homodimerization activity
GO:0043531 ADP binding
Biological Process
GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process
GO:0006167 AMP biosynthetic process
GO:0009116 nucleoside metabolic process
GO:0009165 nucleotide biosynthetic process
GO:0016310 phosphorylation
GO:0031100 organ regeneration
Cellular Component
GO:0002189 ribose phosphate diphosphokinase complex
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_189085
Disease pathway
REACT_188937
Metabolism pathway
REACT_261206
5-Phosphoribose 1-diphosphate biosynthesis pathway
REACT_203949
Glycogen storage diseases pathway
REACT_203841
Myoclonic epilepsy of Lafora pathway
REACT_248571
Metabolism of carbohydrates pathway
KEGG
mmu00030
Pentose phosphate pathway pathway
mmu00230
Purine metabolism pathway
INOH
PID NCI
Cross-References
SwissProt Q9D7G0
TrEMBL Q3UYQ0
UniProt Splice Variant
Entrez Gene 19139
UniGene Mm.287178 Mm.417356
RefSeq NM_021463
OMIM
CCDS CCDS30439
HPRD
IMGT
MGI ID MGI:97775
MGI Symbol Prps1
EMBL AB025048 AK009265 AK011304 AK089009 AK134500 AK165524 AK165987 AK166856 AL672297 BC054772 BC110357 CH466616
GenPept AAH54772 AAI10358 BAA84686 BAB26181 BAB27530 BAC40697 BAE22162 BAE38237 BAE38503 BAE39073 CAM14818 EDL23928 EDL23929
RNA Seq Atlas 19139

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca