Version 5.4
Mus musculus Gene: Cyp4a12a
Summary
InnateDB Gene IDBG-175924.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cyp4a12a
Gene Name cytochrome P450, family 4, subfamily a, polypeptide 12a
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000066071
Encoded Proteins
IDBP-175926
cytochrome P450, family 4, subfamily a, polypeptide 12a
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 4:115299046-115332815
Strand Forward strand
Band D1
Transcripts
ENSMUST00000084343 ENSMUSP00000081370
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004497 monooxygenase activity
GO:0005506 iron ion binding
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0018685 alkane 1-monooxygenase activity
GO:0020037 heme binding
GO:0070330 aromatase activity
Biological Process
GO:0006631 fatty acid metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005789 endoplasmic reticulum membrane
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_232159
Cytochrome P450 - arranged by substrate type pathway
REACT_249802
Phase 1 - Functionalization of compounds pathway
REACT_256522
Fatty acid, triacylglycerol, and ketone body metabolism pathway
REACT_188937
Metabolism pathway
REACT_196572
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) pathway
REACT_232291
Metabolism of lipids and lipoproteins pathway
REACT_257219
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) pathway
REACT_237452
Fatty acids pathway
REACT_198602
PPARA activates gene expression pathway
REACT_232343
Biological oxidations pathway
REACT_188625
Arachidonic acid metabolism pathway
KEGG
mmu00830
Retinol metabolism pathway
mmu00590
Arachidonic acid metabolism pathway
mmu03320
PPAR signaling pathway pathway
mmu00071
Fatty acid degradation pathway
mmu04270
Vascular smooth muscle contraction pathway
INOH
PID NCI
Cross-References
SwissProt Q91WL5
TrEMBL O35650 Q06767
UniProt Splice Variant
Entrez Gene 277753
UniGene Mm.276106
RefSeq NM_177406
OMIM
CCDS CCDS18489
HPRD
IMGT
MGI ID MGI:88612
MGI Symbol Cyp4a12a
EMBL AK144260 AL627182 AL627227 BC014721 BC025936 BC026582 BC031141 BC033924 CH466552 X71479 Y10221 Y10222
GenPept AAH14721 AAH25936 AAH26582 AAH31141 AAH33924 BAE25803 CAA50585 CAA71269 CAM18400 CAM21083 EDL30651
RNA Seq Atlas 277753

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca