Mus musculus Gene: Siglecg
Summary
InnateDB Gene IDBG-176715.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Siglecg
Gene Name sialic acid binding Ig-like lectin G
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000030468
Encoded Proteins
sialic acid binding Ig-like lectin G
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation
Summary
Siglecg is a member of the SIGLEC protein family that recognize sialoside-based patterns and responds selectively to danger associated molecular patterns (DAMPs) to initiate limited innate response.
Siglecg expression is upregulated by RNA viruses to suppress the RIG-I anti-viral signalling pathway.
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 7:43408204-43418358
Strand Forward strand
Band B3
Transcripts
ENSMUST00000005592 ENSMUSP00000005592
ENSMUST00000154322
ENSMUST00000124502
ENSMUST00000131744
ENSMUST00000124885
ENSMUST00000123042
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated
Total 8 [view]
Protein-Protein 7 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0002244 hematopoietic progenitor cell differentiation
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0016021 integral component of membrane
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.24444 Mm.416162
RefSeq NM_172900 XM_006540863
OMIM
CCDS CCDS52221
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas