Version 5.4
Mus musculus Gene: Pphln1
Summary
InnateDB Gene IDBG-176781.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pphln1
Gene Name periphilin 1
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000036167
Encoded Proteins
IDBP-176783
periphilin 1
IDBP-176785
periphilin 1
IDBP-262779
periphilin 1
IDBP-622528
periphilin 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000134283:
The protein encoded by this gene is one of the several proteins that become sequentially incorporated into the cornified cell envelope during the terminal differentiation of keratinocyte at the outer layers of epidermis. This protein interacts with periplakin, which is known as a precursor of the cornified cell envelope. The cellular localization pattern and insolubility of this protein suggest that it may play a role in epithelial differentiation and contribute to epidermal integrity and barrier formation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:93398350-93491913
Strand Forward strand
Band E3
Transcripts
ENSMUST00000068457 ENSMUSP00000068165
ENSMUST00000049122 ENSMUSP00000042762
ENSMUST00000109256 ENSMUSP00000104879
ENSMUST00000165935 ENSMUSP00000131121
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 18 [view]
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000134283
View Gene Order
ENSBTAG00000008595
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.415853 Mm.455299 Mm.474730 Mm.74208
RefSeq NM_001083114 NM_001285863 NM_001285864 NM_146062 NM_175363 XM_006520850 XM_006520851 XM_006520852 XM_006520855 XM_006520856 XM_006520857 XM_006520860 XM_006520861
OMIM
CCDS CCDS27767 CCDS27768 CCDS37181
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca