Version 5.4
Mus musculus Gene: Smn1
Summary
InnateDB Gene IDBG-177072.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Smn1
Gene Name survival motor neuron 1
Synonyms AI849087; Gemin1; Smn
Species Mus musculus
Ensembl Gene ENSMUSG00000021645
Encoded Proteins
IDBP-177074
survival motor neuron 1
IDBP-177078
survival motor neuron 1
IDBP-535789
survival motor neuron 1
IDBP-536705
survival motor neuron 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 13:100124852-100137690
Strand Forward strand
Band D1
Transcripts
ENSMUST00000022147 ENSMUSP00000022147
ENSMUST00000091321 ENSMUSP00000088871
ENSMUST00000134514
ENSMUST00000140745 ENSMUSP00000118509
ENSMUST00000143937 ENSMUSP00000119381
ENSMUST00000125572
ENSMUST00000151389
ENSMUST00000147306
ENSMUST00000135355
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0000387 spliceosomal snRNP assembly
GO:0006397 mRNA processing
GO:0007019 microtubule depolymerization
GO:0007409 axonogenesis
GO:0042307 positive regulation of protein import into nucleus
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0015030 Cajal body
GO:0030018 Z disc
GO:0032797 SMN complex
GO:0034719 SMN-Sm protein complex
GO:0097504 Gemini of coiled bodies
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_224866
Metabolism of non-coding RNA pathway
REACT_206812
snRNP Assembly pathway
REACT_233572
Gene Expression pathway
KEGG
mmu03013
RNA transport pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.2025 Mm.407706
RefSeq NM_001252629 NM_011420
OMIM
CCDS CCDS26725
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca