Version 5.4
Mus musculus Gene: Klk12
Summary
InnateDB Gene IDBG-177396.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Klk12
Gene Name kallikrein related-peptidase 12
Synonyms 2310008B01Rik; AI324852; KLK-L5
Species Mus musculus
Ensembl Gene ENSMUSG00000044430
Encoded Proteins
IDBP-177398
kallikrein related-peptidase 12
IDBP-265547
kallikrein related-peptidase 12
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000186474:
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in three transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:43768897-43773576
Strand Forward strand
Band B3
Transcripts
ENSMUST00000014063 ENSMUSP00000014063
ENSMUST00000107970 ENSMUSP00000103604
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004252 serine-type endopeptidase activity
GO:0008233 peptidase activity
GO:0008236 serine-type peptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000186474
View Gene Order
ENSBTAG00000030484
Not yet available
Cross-References
SwissProt
TrEMBL B2RVZ0 Q9CV76
UniProt Splice Variant
Entrez Gene 69511
UniGene Mm.20163
RefSeq NM_027097 XM_006541174
OMIM
CCDS CCDS52226
HPRD
IMGT
MGI ID MGI:1916761
MGI Symbol Klk12
EMBL AC151989 AK009217 BC147442 BC147463 CH466603
GenPept AAI47443 AAI47464 BAB26143 EDL22675
RNA Seq Atlas 69511

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca