Mus musculus Gene: Mrps6
Summary
InnateDB Gene IDBG-177486.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mrps6
Gene Name mitochondrial ribosomal protein S6
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000039680
Encoded Proteins
mitochondrial ribosomal protein S6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000243927:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S6P family. Pseudogenes corresponding to this gene are found on chromosomes 1p and 12q. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:92058270-92112227
Strand Forward strand
Band C4
Transcripts
ENSMUST00000047429 ENSMUSP00000037631
ENSMUST00000138961
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005739 mitochondrion
GO:0005840 ribosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Mitochondrial translation pathway
Organelle biogenesis and maintenance pathway
Mitochondrial translation elongation pathway
Mitochondrial translation initiation pathway
Mitochondrial translation termination pathway
KEGG
Ribosome pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Organelle biogenesis and maintenance pathway
Mitochondrial translation pathway
Mitochondrial translation initiation pathway
Mitochondrial translation termination pathway
Mitochondrial translation elongation pathway
KEGG
Ribosome pathway
INOH
PID NCI
Cross-References
SwissProt P58064
TrEMBL Q3TLQ4
UniProt Splice Variant
Entrez Gene 121022
UniGene Mm.396129
RefSeq NM_080456
OMIM
CCDS CCDS28332
HPRD
IMGT
MGI ID MGI:2153111
MGI Symbol Mrps6
EMBL AB049943 AK165590 AK166374 AK167304 AK167316 AY061856 BC027271
GenPept AAH27271 AAL35740 BAB40996 BAE38278 BAE38738 BAE39408 BAE39418
RNA Seq Atlas 121022