Version 5.4
Mus musculus Gene: Lrch2
Summary
InnateDB Gene IDBG-177522.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Lrch2
Gene Name leucine-rich repeats and calponin homology (CH) domain containing 2
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000031290
Encoded Proteins
IDBP-255176
leucine-rich repeats and calponin homology (CH) domain containing 2
IDBP-540307
leucine-rich repeats and calponin homology (CH) domain containing 2
IDBP-536076
leucine-rich repeats and calponin homology (CH) domain containing 2
IDBP-540145
leucine-rich repeats and calponin homology (CH) domain containing 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000130224:
This gene encodes a member of the leucine-rich repeat and calponin homology domain-containing protein family. These family members contain multiple N-terminal leucine-rich repeats, in addition to a C-terminal calponin homology domain, a type of domain that mediates interactions with actin filaments. These proteins are conserved across animal species, and studies of a similar Drosophila protein indicate a function as a cytoskeletal scaffolding protein. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome X:147470375-147554081
Strand Reverse strand
Band F2
Transcripts
ENSMUST00000112819 ENSMUSP00000108438
ENSMUST00000152838 ENSMUSP00000121128
ENSMUST00000136789 ENSMUSP00000123633
ENSMUST00000134265
ENSMUST00000137665 ENSMUSP00000117458
ENSMUST00000151730
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000130224
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.30506 Mm.474862
RefSeq NM_001081173 XM_006528790
OMIM
CCDS CCDS41160
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca