Version 5.4
Mus musculus Gene: Eif4e2
Summary
InnateDB Gene IDBG-177898.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Eif4e2
Gene Name eukaryotic translation initiation factor 4E member 2
Synonyms 2700069E09Rik; AI036339; AV129531; D0H0S6743E; Eif4el3
Species Mus musculus
Ensembl Gene ENSMUSG00000026254
Encoded Proteins
IDBP-177900
eukaryotic translation initiation factor 4E member 2
IDBP-177904
eukaryotic translation initiation factor 4E member 2
IDBP-254307
eukaryotic translation initiation factor 4E member 2
IDBP-254309
eukaryotic translation initiation factor 4E member 2
IDBP-254311
eukaryotic translation initiation factor 4E member 2
IDBP-254313
eukaryotic translation initiation factor 4E member 2
IDBP-254315
eukaryotic translation initiation factor 4E member 2
IDBP-713774
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000135930:
Gene Information
Type Protein coding
Genomic Location Chromosome 1:87213914-87240488
Strand Forward strand
Band C5
Transcripts
ENSMUST00000076362 ENSMUSP00000075699
ENSMUST00000050876 ENSMUSP00000053403
ENSMUST00000113235 ENSMUSP00000108861
ENSMUST00000113233 ENSMUSP00000108859
ENSMUST00000113232 ENSMUSP00000108858
ENSMUST00000113231 ENSMUSP00000108857
ENSMUST00000113230 ENSMUSP00000108856
ENSMUST00000123735 ENSMUSP00000137771
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 18 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0003743 translation initiation factor activity
GO:0005515 protein binding
GO:0031625 ubiquitin protein ligase binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0001701 in utero embryonic development
GO:0006413 translational initiation
GO:0017148 negative regulation of translation
Cellular Component
GO:0005737 cytoplasm
GO:0005845 mRNA cap binding complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000135930
View Gene Order
ENSBTAG00000010598
Not yet available
Pathways
NETPATH
REACTOME
REACT_233584
Cytokine Signaling in Immune system pathway
REACT_198535
Antiviral mechanism by IFN-stimulated genes pathway
REACT_198533
ISG15 antiviral mechanism pathway
REACT_230745
Immune System pathway
REACT_198666
Interferon Signaling pathway
KEGG
mmu04910
Insulin signaling pathway pathway
mmu04150
mTOR signaling pathway pathway
mmu03013
RNA transport pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_115831
ISG15 antiviral mechanism pathway
REACT_115676
Antiviral mechanism by IFN-stimulated genes pathway
REACT_75790
Cytokine Signaling in Immune system pathway
REACT_25229
Interferon Signaling pathway
REACT_6900
Immune System pathway
KEGG
hsa04150
mTOR signaling pathway pathway
hsa04910
Insulin signaling pathway pathway
hsa03013
RNA transport pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL D3Z729
UniProt Splice Variant
Entrez Gene 26987
UniGene Mm.227183 Mm.398174 Mm.409275
RefSeq XM_006529671 NM_001039169 NM_001039170 NM_023314 XM_006529674
OMIM
CCDS CCDS15130 CCDS15131 CCDS35652
HPRD
IMGT
MGI ID MGI:1914440
MGI Symbol Eif4e2
EMBL AC102611
GenPept
RNA Seq Atlas 26987

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca