Version 5.4
Mus musculus Gene: Hsd3b3
Summary
InnateDB Gene IDBG-178233.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Hsd3b3
Gene Name hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3
Synonyms 9030618K22Rik; AI790201
Species Mus musculus
Ensembl Gene ENSMUSG00000062410
Encoded Proteins
IDBP-178235
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3
IDBP-178237
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3
IDBP-267563
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3
IDBP-267565
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3
IDBP-537804
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3
IDBP-542017
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3
IDBP-541068
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3
IDBP-542480
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3
IDBP-532556
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 3:98741524-98763128
Strand Reverse strand
Band F2.2
Transcripts
ENSMUST00000090743 ENSMUSP00000088246
ENSMUST00000094050 ENSMUSP00000091592
ENSMUST00000107019 ENSMUSP00000102633
ENSMUST00000107018 ENSMUSP00000102632
ENSMUST00000148578 ENSMUSP00000122210
ENSMUST00000135706 ENSMUSP00000118462
ENSMUST00000125483 ENSMUSP00000116052
ENSMUST00000146196 ENSMUSP00000121360
ENSMUST00000137008 ENSMUSP00000119333
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity
GO:0004769 steroid delta-isomerase activity
GO:0008831 dTDP-4-dehydrorhamnose reductase activity
GO:0016491 oxidoreductase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0050662 coenzyme binding
Biological Process
GO:0006694 steroid biosynthetic process
GO:0008152 metabolic process
GO:0009058 biosynthetic process
GO:0044237 cellular metabolic process
GO:0045226 extracellular polysaccharide biosynthetic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005743 mitochondrial inner membrane
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_207160
Glucocorticoid biosynthesis pathway
REACT_188937
Metabolism pathway
REACT_232291
Metabolism of lipids and lipoproteins pathway
REACT_204887
Mineralocorticoid biosynthesis pathway
REACT_220332
Androgen biosynthesis pathway
REACT_220061
Metabolism of steroid hormones and vitamin D pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001012306 NM_001161742 NM_001161743 NM_001161744 NM_001161745 XM_006501039 XM_006501040 XM_006501041 XM_006501042
OMIM
CCDS CCDS17668 CCDS51016
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca