Version 5.4
Mus musculus Gene: H2-Q10
Summary
InnateDB Gene IDBG-178272.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol H2-Q10
Gene Name histocompatibility 2, Q region locus 10
Synonyms H-2Q10; Q10; Qa10
Species Mus musculus
Ensembl Gene ENSMUSG00000067235
Encoded Proteins
IDBP-178274
histocompatibility 2, Q region locus 10
IDBP-628203
histocompatibility 2, Q region locus 10
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 17:35470089-35474563
Strand Forward strand
Band B1
Transcripts
ENSMUST00000068291 ENSMUSP00000066419
ENSMUST00000174525 ENSMUSP00000134163
ENSMUST00000174589
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005102 receptor binding
GO:0005515 protein binding
GO:0042605 peptide antigen binding
Biological Process
GO:0001916 positive regulation of T cell mediated cytotoxicity
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0005886 plasma membrane
GO:0030670 phagocytic vesicle membrane
GO:0042612 MHC class I protein complex
GO:0071556 integral component of lumenal side of endoplasmic reticulum membrane
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_236645
Class I MHC mediated antigen processing & presentation pathway
REACT_202937
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell pathway
REACT_233584
Cytokine Signaling in Immune system pathway
REACT_230745
Immune System pathway
REACT_199105
ER-Phagosome pathway pathway
REACT_199112
Endosomal/Vacuolar pathway pathway
REACT_198660
Interferon gamma signaling pathway
REACT_198666
Interferon Signaling pathway
REACT_199113
Antigen processing-Cross presentation pathway
REACT_229531
Adaptive Immune System pathway
REACT_246972
Antigen Presentation: Folding, assembly and peptide loading of class I MHC pathway
KEGG
mmu04514
Cell adhesion molecules (CAMs) pathway
mmu04940
Type I diabetes mellitus pathway
mmu04612
Antigen processing and presentation pathway
mmu05330
Allograft rejection pathway
mmu05332
Graft-versus-host disease pathway
mmu05320
Autoimmune thyroid disease pathway
mmu04144
Endocytosis pathway
mmu05416
Viral myocarditis pathway
mmu04145
Phagosome pathway
INOH
PID NCI
Cross-References
SwissProt P01898
TrEMBL O19454
UniProt Splice Variant
Entrez Gene 15007
UniGene Mm.400772 Mm.88795
RefSeq NM_010391 XM_006523696 XM_006525327 XM_006536539 XM_006537273
OMIM
CCDS CCDS37599
HPRD
IMGT
MGI ID MGI:95929
MGI Symbol H2-Q10
EMBL AK131620 BC011215 J00392 K00614 K01205 K01207 M12484 X16206 X16426
GenPept AAA39540 AAA39574 AAA39676 AAA39681 AAH11215 BAE20725 CAA34326 CAA34449
RNA Seq Atlas 15007

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca