Version 5.4
Mus musculus Gene: Klk1b4
Summary
InnateDB Gene IDBG-178304.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Klk1b4
Gene Name kallikrein 1-related pepidase b4
Synonyms mGk-4; Ngfa
Species Mus musculus
Ensembl Gene ENSMUSG00000066513
Encoded Proteins
IDBP-178306
kallikrein 1-related pepidase b4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 7:44207435-44211754
Strand Forward strand
Band B3
Transcripts
ENSMUST00000077354 ENSMUSP00000076576
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004252 serine-type endopeptidase activity
GO:0005057 receptor signaling protein activity
GO:0008083 growth factor activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
GO:0007264 small GTPase mediated signal transduction
GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity
Cellular Component
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_199000
Activation of Matrix Metalloproteinases pathway
REACT_206066
Extracellular matrix organization pathway
REACT_247926
Metabolism of proteins pathway
REACT_235886
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) pathway
REACT_199052
Degradation of the extracellular matrix pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt P00757
TrEMBL
UniProt Splice Variant
Entrez Gene 18048
UniGene
RefSeq NM_010915
OMIM
CCDS CCDS21200
HPRD
IMGT
MGI ID MGI:97320
MGI Symbol Klk1b4
EMBL BC034518 M11434 X01800 X01801
GenPept AAA39819 AAH34518 CAA25931 CAA25932
RNA Seq Atlas 18048

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca