Version 5.4
Mus musculus Gene: Dcaf17
Summary
InnateDB Gene IDBG-178371.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dcaf17
Gene Name DDB1 and CUL4 associated factor 17
Synonyms 2810055O12Rik; 4833418A01Rik; A030004A10Rik; A930009G19Rik; AI448937
Species Mus musculus
Ensembl Gene ENSMUSG00000041966
Encoded Proteins
IDBP-178377
DDB1 and CUL4 associated factor 17
IDBP-178379
DDB1 and CUL4 associated factor 17
IDBP-256571
DDB1 and CUL4 associated factor 17
IDBP-256573
DDB1 and CUL4 associated factor 17
IDBP-541429
DDB1 and CUL4 associated factor 17
IDBP-537415
DDB1 and CUL4 associated factor 17
IDBP-535497
DDB1 and CUL4 associated factor 17
IDBP-536891
DDB1 and CUL4 associated factor 17
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000115827:
This gene encodes a nuclear transmembrane protein that associates with cullin 4A/damaged DNA binding protein 1 ubiquitin ligase complex. Mutations in this gene are associated with Woodhouse-Sakati syndrome. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:71055328-71099142
Strand Forward strand
Band C2
Transcripts
ENSMUST00000064141 ENSMUSP00000065624
ENSMUST00000102701 ENSMUSP00000099762
ENSMUST00000112167 ENSMUSP00000107791
ENSMUST00000112159 ENSMUSP00000107785
ENSMUST00000130292 ENSMUSP00000117830
ENSMUST00000154704 ENSMUSP00000120016
ENSMUST00000135357 ENSMUSP00000118011
ENSMUST00000136299 ENSMUSP00000114459
ENSMUST00000132619
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0008150 biological_process
GO:0016567 protein ubiquitination
Cellular Component
GO:0005730 nucleolus
GO:0016021 integral component of membrane
GO:0080008 Cul4-RING E3 ubiquitin ligase complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000115827
View Gene Order
ENSBTAG00000007683
Not yet available
Cross-References
SwissProt
TrEMBL B0R0U2
UniProt Splice Variant
Entrez Gene 75763
UniGene Mm.281668 Mm.408597 Mm.489700
RefSeq NM_001165980 NM_001165981 NM_001165982 NM_198005 XM_006500339 XM_006500340 XM_006500341
OMIM
CCDS CCDS16111 CCDS50601 CCDS50602
HPRD
IMGT
MGI ID MGI:1923013
MGI Symbol Dcaf17
EMBL AL929228
GenPept
RNA Seq Atlas 75763

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca