Version 5.4
| Homo sapiens Gene: KLRB1 | |||||||
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| Summary | |||||||
| InnateDB Gene | IDBG-17865.6 | ||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
| Gene Symbol | KLRB1 | ||||||
| Gene Name | killer cell lectin-like receptor subfamily B, member 1 | ||||||
| Synonyms | CD161; CLEC5B; hNKR-P1A; NKR; NKR-P1; NKR-P1A; NKRP1A | ||||||
| Species | Homo sapiens | ||||||
| Ensembl Gene | ENSG00000111796 | ||||||
| Encoded Proteins |
killer cell lectin-like receptor subfamily B, member 1
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||
| Entrez Gene | |||||||
| Summary |
Natural killer (NK) cells are lymphocytes that mediate cytotoxicity and secrete cytokines after immune stimulation. Several genes of the C-type lectin superfamily, including the rodent NKRP1 family of glycoproteins, are expressed by NK cells and may be involved in the regulation of NK cell function. The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins, a transmembrane domain, and a cytoplasmic domain. The KLRB1 protein is classified as a type II membrane protein because it has an external C terminus. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||
| Type | Protein coding | ||||||
| Genomic Location | Chromosome 12:9594551-9607886 | ||||||
| Strand | Reverse strand | ||||||
| Band | p13.31 | ||||||
| Transcripts |
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| Interactions | |||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||
| No orthologs found for this gene | |||||||
| Pathways | |||||||
| NETPATH | |||||||
| REACTOME | |||||||
| KEGG |
Malaria pathway
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| INOH | |||||||
| PID NCI | |||||||
| Cross-References | |||||||
| SwissProt | Q12918 | ||||||
| TrEMBL | |||||||
| UniProt Splice Variant | |||||||
| Entrez Gene | 3820 | ||||||
| UniGene | Hs.169824 | ||||||
| RefSeq | NM_002258 | ||||||
| HUGO | HGNC:6373 | ||||||
| OMIM | 602890 | ||||||
| CCDS | CCDS8601 | ||||||
| HPRD | |||||||
| IMGT | |||||||
| EMBL | BC113997 BC114516 U11276 | ||||||
| GenPept | AAA21605 AAI13998 AAI14517 | ||||||
| RNA Seq Atlas | 3820 | ||||||