Version 5.4
Mus musculus Gene: Abcb5
Summary
InnateDB Gene IDBG-178891.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Abcb5
Gene Name ATP-binding cassette, sub-family B (MDR/TAP), member 5
Synonyms 9230106F14Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000072791
Encoded Proteins
IDBP-178942
ATP-binding cassette, sub-family B (MDR/TAP), member 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000004846:
ABCB5 belongs to the ATP-binding cassette (ABC) transporter superfamily of integral membrane proteins. These proteins participate in ATP-dependent transmembrane transport of structurally diverse molecules ranging from small ions, sugars, and peptides to more complex organic molecules (Chen et al., 2005 [PubMed 15760339]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:118867824-118966421
Strand Reverse strand
Band F2
Transcripts
ENSMUST00000100982
ENSMUST00000035515 ENSMUSP00000046177
ENSMUST00000177311
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0005524 ATP binding
GO:0015562 efflux transmembrane transporter activity
GO:0016887 ATPase activity
GO:0017111 nucleoside-triphosphatase activity
GO:0042626 ATPase activity, coupled to transmembrane movement of substances
Biological Process
GO:0002481 antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
GO:0002485 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent
GO:0002489 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent
GO:0002591 positive regulation of antigen processing and presentation of peptide antigen via MHC class I
GO:0006200 ATP catabolic process
GO:0006810 transport
GO:0042391 regulation of membrane potential
GO:0055085 transmembrane transport
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000004846
View Gene Order
ENSBTAG00000002595
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu02010
ABC transporters pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_15480
ABC-family proteins mediated transport pathway
REACT_15518
Transmembrane transport of small molecules pathway
KEGG
hsa02010
ABC transporters pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL B5X0E4 Q9CTU3
UniProt Splice Variant
Entrez Gene 77706
UniGene Mm.261496
RefSeq NM_029961 XM_006516370
OMIM
CCDS CCDS49198
HPRD
IMGT
MGI ID MGI:1924956
MGI Symbol Abcb5
EMBL AC126277 AC131717 AK020318 AY766239
GenPept AAX11686 BAB32070
RNA Seq Atlas 77706

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca