Version 5.4
Mus musculus Gene: Dclre1a
Summary
InnateDB Gene IDBG-178964.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dclre1a
Gene Name DNA cross-link repair 1A, PSO2 homolog (S. cerevisiae)
Synonyms 2810043H12Rik; AU022226; mKIAA0086; Pso2; Smn1a; Snm1
Species Mus musculus
Ensembl Gene ENSMUSG00000025077
Encoded Proteins
IDBP-790019
DNA cross-link repair 1A, PSO2 homolog (S. cerevisiae)
IDBP-790020
DNA cross-link repair 1A, PSO2 homolog (S. cerevisiae)
IDBP-790021
DNA cross-link repair 1A, PSO2 homolog (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000198924:
This gene encodes a conserved protein that is involved in the repair of DNA interstrand cross-links. DNA cross-links suppress transcription, replication, and DNA segregation. The encoded protein is a regulator of the mitotic cell cycle checkpoint. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:56529167-56548222
Strand Reverse strand
Band D2
Transcripts
ENSMUST00000183143 ENSMUSP00000138537
ENSMUST00000182058
ENSMUST00000182276 ENSMUSP00000138290
ENSMUST00000183216
ENSMUST00000181992
ENSMUST00000182059 ENSMUSP00000138364
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016787 hydrolase activity
Biological Process
GO:0006289 nucleotide-excision repair
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000198924
View Gene Order
ENSBTAG00000020193
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_018831 XM_006527216 XM_006527217 XM_006527218
OMIM
CCDS CCDS29917
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca