Version 5.4
Mus musculus Gene: Ppp1r18
Summary
InnateDB Gene IDBG-179289.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ppp1r18
Gene Name protein phosphatase 1, regulatory subunit 18
Synonyms 2310014H01Rik; AA407849; AI450394
Species Mus musculus
Ensembl Gene ENSMUSG00000034595
Encoded Proteins
IDBP-253089
RIKEN cDNA 2310014H01 gene
IDBP-538370
RIKEN cDNA 2310014H01 gene
IDBP-537316
RIKEN cDNA 2310014H01 gene
IDBP-533431
RIKEN cDNA 2310014H01 gene
IDBP-788884
protein phosphatase 1, regulatory subunit 18
IDBP-788885
protein phosphatase 1, regulatory subunit 18
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000146112:
Protein phosphatase-1 (PP1; see MIM 176875) interacts with regulatory subunits that target the enzyme to different cellular locations and change its activity toward specific substrates. Phostensin is a regulatory subunit that targets PP1 to F-actin (see MIM 102610) cytoskeleton (Kao et al., 2007 [PubMed 17374523]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:35865593-35875596
Strand Forward strand
Band B1
Transcripts
ENSMUST00000113814 ENSMUSP00000109445
ENSMUST00000127442 ENSMUSP00000115753
ENSMUST00000144382 ENSMUSP00000116100
ENSMUST00000122899 ENSMUSP00000120343
ENSMUST00000190496 ENSMUSP00000140652
ENSMUST00000187690 ENSMUSP00000141094
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003779 actin binding
GO:0019902 phosphatase binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000146112
View Gene Order
ENSBTAG00000039695
Not yet available
Cross-References
SwissProt Q8BQ30
TrEMBL
UniProt Splice Variant
Entrez Gene 76448
UniGene Mm.359982 Mm.391732
RefSeq NM_001146710 NM_001146711 NM_175242 XM_006525092 XM_006525093 XM_006525094 XM_006536702 XM_006536703 XM_006537433 XM_006537434
OMIM
CCDS CCDS50094
HPRD
IMGT
MGI ID MGI:1923698
MGI Symbol Ppp1r18
EMBL AK009340 AK051656 AK149943 BC025573 CR974451
GenPept AAH25573 BAC25252 BAC34706 BAE29185 CAX15752 CAX15753
RNA Seq Atlas 76448

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca