Version 5.4
Mus musculus Gene: H2-T22
Summary
InnateDB Gene IDBG-180348.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol H2-T22
Gene Name histocompatibility 2, T region locus 22
Synonyms H-2T9
Species Mus musculus
Ensembl Gene ENSMUSG00000056116
Encoded Proteins
IDBP-180352
histocompatibility 2, T region locus 22
IDBP-180354
histocompatibility 2, T region locus 22
IDBP-180356
histocompatibility 2, T region locus 22
IDBP-628351
histocompatibility 2, T region locus 22
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 17:36037128-36042747
Strand Reverse strand
Band B1
Transcripts
ENSMUST00000080015 ENSMUSP00000078927
ENSMUST00000077960 ENSMUSP00000077111
ENSMUST00000058801 ENSMUSP00000056041
ENSMUST00000172633
ENSMUST00000173280 ENSMUSP00000134019
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0042605 peptide antigen binding
Biological Process
GO:0001916 positive regulation of T cell mediated cytotoxicity
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0042612 MHC class I protein complex
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
KEGG
mmu04514
Cell adhesion molecules (CAMs) pathway
mmu04940
Type I diabetes mellitus pathway
mmu04612
Antigen processing and presentation pathway
mmu05330
Allograft rejection pathway
mmu05332
Graft-versus-host disease pathway
mmu05320
Autoimmune thyroid disease pathway
mmu04144
Endocytosis pathway
mmu05416
Viral myocarditis pathway
mmu04145
Phagosome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL A7VMS4 Q31615 Q3TSX0
UniProt Splice Variant
Entrez Gene 15051
UniGene Mm.195061 Mm.397112
RefSeq NM_010399 XM_006523701 NM_010397 XM_006523702
OMIM
CCDS CCDS37608
HPRD
IMGT
MGI ID MGI:95956
MGI Symbol H2-T22
EMBL AB359229 AC112970 AK133985 AK161744 M35243 M35245
GenPept AAA39690 AAA39691 BAE21968 BAE36555 BAF76149
RNA Seq Atlas 15039 15051

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca