InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Atp5g3

Summary

InnateDB Gene

IDBG-180725.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Atp5g3

Gene Name

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)

Synonyms

Species

Mus musculus

Ensembl Gene

ENSMUSG00000018770

Encoded Proteins

IDBP-180727

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)

IDBP-256938

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000154518:
This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene is one of three genes that encode subunit c of the proton channel. Each of the three genes have distinct mitochondrial import sequences but encode the identical mature protein. Alternatively spliced transcript variants encoding different proteins have been identified. [provided by RefSeq, Jun 2010]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 2:73908447-73911326

Strand

Reverse strand

Band

Transcripts

ENSMUST00000018914	ENSMUSP00000018914
ENSMUST00000111996	ENSMUSP00000107627
ENSMUST00000142768
ENSMUST00000131045
ENSMUST00000155474

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008289	lipid binding
GO:0015078	hydrogen ion transmembrane transporter activity

Biological Process

GO:0008150	biological_process
GO:0015986	ATP synthesis coupled proton transport
GO:0015991	ATP hydrolysis coupled proton transport

Cellular Component

GO:0005739	mitochondrion
GO:0016021	integral component of membrane
GO:0031966	mitochondrial membrane
GO:0033177	proton-transporting two-sector ATPase complex, proton-transporting domain
GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)