InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Rnd1

Summary

InnateDB Gene

IDBG-180901.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Rnd1

Gene Name

Rho family GTPase 1

Synonyms

Species

Mus musculus

Ensembl Gene

ENSMUSG00000054855

Encoded Proteins

IDBP-180903

Rho family GTPase 1

IDBP-263014

Rho family GTPase 1

IDBP-400933

Rho family GTPase 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000172602:
Members of the Rho GTPase family, such as RND1, regulate the organization of the actin cytoskeleton in response to extracellular growth factors (Nobes et al., 1998 [PubMed 9531558]).[supplied by OMIM, Mar 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 15:98663421-98677461

Strand

Reverse strand

Band

Transcripts

ENSMUST00000003451	ENSMUSP00000003451
ENSMUST00000109149	ENSMUSP00000104777
ENSMUST00000120997	ENSMUSP00000113830

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	13 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005102	receptor binding
GO:0005515	protein binding
GO:0005525	GTP binding

Biological Process

GO:0006184	GTP catabolic process
GO:0007015	actin filament organization
GO:0007162	negative regulation of cell adhesion
GO:0007165	signal transduction
GO:0007264	small GTPase mediated signal transduction
GO:0015031	protein transport
GO:0016322	neuron remodeling