Version 5.4
Mus musculus Gene: Tuba1b
Summary
InnateDB Gene IDBG-181938.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tuba1b
Gene Name tubulin, alpha 1B
Synonyms Tuba2
Species Mus musculus
Ensembl Gene ENSMUSG00000023004
Encoded Proteins
IDBP-181940
tubulin, alpha 1B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000123416:
Gene Information
Type Protein coding
Genomic Location Chromosome 15:98931425-98934565
Strand Reverse strand
Band F1
Transcripts
ENSMUST00000077577 ENSMUSP00000076777
ENSMUST00000140969
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
They are also associated with 63 interaction(s) predicted by orthology.
Experimentally validated
Total 18 [view]
Protein-Protein 18 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 63 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003725 double-stranded RNA binding
GO:0003924 GTPase activity
GO:0005200 structural constituent of cytoskeleton
GO:0005515 protein binding
GO:0005525 GTP binding
Biological Process
GO:0000226 microtubule cytoskeleton organization
GO:0006184 GTP catabolic process
GO:0006457 protein folding
GO:0051258 protein polymerization
GO:0071353 cellular response to interleukin-4
Cellular Component
GO:0005829 cytosol
GO:0005874 microtubule
GO:0005881 cytoplasmic microtubule
GO:0043234 protein complex
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000123416
View Gene Order
ENSBTAG00000012244
Not yet available
Pathways
NETPATH
REACTOME
REACT_245720
Recruitment of mitotic centrosome proteins and complexes pathway
REACT_224389
Gap junction trafficking and regulation pathway
REACT_240530
G2/M Transition pathway
REACT_249770
Cell Cycle, Mitotic pathway
REACT_224553
Hemostasis pathway
REACT_207679
Separation of Sister Chromatids pathway
REACT_257923
Recycling pathway of L1 pathway
REACT_227366
Gap junction assembly pathway
REACT_269412
Hedgehog 'off' state pathway
REACT_198961
Resolution of Sister Chromatid Cohesion pathway
REACT_209837
Membrane Trafficking pathway
REACT_258900
Chaperonin-mediated protein folding pathway
REACT_188804
Cell Cycle pathway
REACT_230745
Immune System pathway
REACT_241408
M Phase pathway
REACT_247926
Metabolism of proteins pathway
REACT_246290
Recruitment of NuMA to mitotic centrosomes pathway
REACT_247933
Post-chaperonin tubulin folding pathway pathway
REACT_218773
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane pathway
REACT_199117
Kinesins pathway
REACT_198649
Factors involved in megakaryocyte development and platelet production pathway
REACT_246508
Mitotic G2-G2/M phases pathway
REACT_196550
MHC class II antigen presentation pathway
REACT_260833
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding pathway
REACT_245534
Protein folding pathway
REACT_199403
Mitotic Metaphase and Anaphase pathway
REACT_256756
Mitotic Prometaphase pathway
REACT_261444
Axon guidance pathway
REACT_208406
Transport of connexons to the plasma membrane pathway
REACT_219680
L1CAM interactions pathway
REACT_229531
Adaptive Immune System pathway
REACT_188576
Developmental Biology pathway
REACT_250064
Signaling by Hedgehog pathway
REACT_217189
Gap junction trafficking pathway
REACT_188257
Signal Transduction pathway
REACT_258053
Formation of tubulin folding intermediates by CCT/TriC pathway
REACT_202512
Mitotic Anaphase pathway
REACT_199054
Translocation of GLUT4 to the plasma membrane pathway
REACT_253753
Centrosome maturation pathway
KEGG
mmu04540
Gap junction pathway
mmu04145
Phagosome pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_150425
Resolution of Sister Chromatid Cohesion pathway
REACT_682
Mitotic Prometaphase pathway
REACT_150471
Separation of Sister Chromatids pathway
REACT_15510
Recruitment of NuMA to mitotic centrosomes pathway
REACT_15296
Recruitment of mitotic centrosome proteins and complexes pathway
REACT_121399
MHC class II antigen presentation pathway
REACT_25201
Kinesins pathway
REACT_24970
Factors involved in megakaryocyte development and platelet production pathway
REACT_16967
Post-chaperonin tubulin folding pathway pathway
REACT_16956
Formation of tubulin folding intermediates by CCT/TriC pathway
REACT_11039
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane pathway
REACT_11050
Transport of connexons to the plasma membrane pathway
REACT_9509
Gap junction assembly pathway
REACT_147867
Translocation of GLUT4 to the plasma membrane pathway
REACT_22365
Recycling pathway of L1 pathway
REACT_22205
L1CAM interactions pathway
REACT_16952
Protein folding pathway
REACT_111045
Developmental Biology pathway
REACT_228134
Signaling by Hedgehog pathway
REACT_18266
Axon guidance pathway
REACT_111102
Signal Transduction pathway
REACT_267634
Hedgehog 'off' state pathway
REACT_9411
Gap junction trafficking pathway
REACT_17004
Chaperonin-mediated protein folding pathway
REACT_115566
Cell Cycle pathway
REACT_17015
Metabolism of proteins pathway
REACT_75774
Adaptive Immune System pathway
REACT_6900
Immune System pathway
REACT_17029
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding pathway
REACT_910
M Phase pathway
REACT_1275
Mitotic Anaphase pathway
REACT_15479
Centrosome maturation pathway
REACT_2203
G2/M Transition pathway
REACT_152
Cell Cycle, Mitotic pathway
REACT_21391
Mitotic G2-G2/M phases pathway
REACT_9480
Gap junction trafficking and regulation pathway
REACT_604
Hemostasis pathway
REACT_11123
Membrane Trafficking pathway
REACT_150314
Mitotic Metaphase and Anaphase pathway
REACT_223914
G2/M Transition pathway
REACT_223433
Recycling pathway of L1 pathway
REACT_215067
Factors involved in megakaryocyte development and platelet production pathway
REACT_216366
M Phase pathway
REACT_215526
L1CAM interactions pathway
REACT_212887
Separation of Sister Chromatids pathway
REACT_215084
Mitotic Metaphase and Anaphase pathway
REACT_211185
Mitotic Anaphase pathway
REACT_217718
Translocation of GLUT4 to the plasma membrane pathway
REACT_212196
Hemostasis pathway
REACT_213138
Immune System pathway
REACT_215505
Cell Cycle, Mitotic pathway
REACT_217933
Mitotic G2-G2/M phases pathway
REACT_222513
Kinesins pathway
REACT_203998
Gap junction trafficking pathway
REACT_214934
Cell Cycle pathway
REACT_214353
Signal Transduction pathway
REACT_203284
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding pathway
REACT_207055
Gap junction assembly pathway
REACT_219091
Chaperonin-mediated protein folding pathway
REACT_270061
Hedgehog 'off' state pathway
REACT_203140
Axon guidance pathway
REACT_211133
MHC class II antigen presentation pathway
REACT_213782
Metabolism of proteins pathway
REACT_224535
Gap junction trafficking and regulation pathway
REACT_215331
Recruitment of NuMA to mitotic centrosomes pathway
REACT_215927
Protein folding pathway
REACT_209545
Resolution of Sister Chromatid Cohesion pathway
REACT_214469
Adaptive Immune System pathway
REACT_241835
Signaling by Hedgehog pathway
REACT_204570
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane pathway
REACT_215812
Recruitment of mitotic centrosome proteins and complexes pathway
REACT_210400
Centrosome maturation pathway
REACT_203101
Mitotic Prometaphase pathway
REACT_220423
Transport of connexons to the plasma membrane pathway
REACT_220844
Developmental Biology pathway
REACT_214148
Formation of tubulin folding intermediates by CCT/TriC pathway
REACT_213260
Membrane Trafficking pathway
KEGG
hsa05130
Pathogenic Escherichia coli infection pathway
hsa04540
Gap junction pathway
hsa04145
Phagosome pathway
INOH
PID NCI
hdac_classii_pathway
Signaling events mediated by HDAC Class II
prlsignalingeventspathway
Signaling events mediated by PRL
hdac_classiii_pathway
Signaling events mediated by HDAC Class III
Cross-References
SwissProt P05213
TrEMBL Q99KA2
UniProt Splice Variant
Entrez Gene 22143
UniGene Mm.343377 Mm.392821 Mm.410958 Mm.490379
RefSeq NM_011654
OMIM
CCDS CCDS37195
HPRD
IMGT
MGI ID MGI:107804
MGI Symbol Tuba1b
EMBL AK075955 AK137885 AK150128 AK150179 AK150968 AK151199 AK151809 AK152298 AK153064 AK153254 AK158958 AK164428 AK168770 AK169075 AK169092 AK169130 AK169665 BC002219 BC004790 BC008117 BC063777 BC083120 BC098321 BC108337 BC108394 M13446 M28727
GenPept AAA40500 AAA40507 AAH02219 AAH04790 AAH08117 AAH63777 AAH83120 AAH98321 AAI08338 AAI08395 BAC36080 BAE23512 BAE29327 BAE29362 BAE29999 BAE30196 BAE30708 BAE31107 BAE31690 BAE31845 BAE34741 BAE37783 BAE40606 BAE40860 BAE40875 BAE40909 BAE41287
RNA Seq Atlas 22143

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca