Version 5.4
Mus musculus Gene: Dfnb59
Summary
InnateDB Gene IDBG-182150.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dfnb59
Gene Name deafness, autosomal recessive 59 (human)
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000075267
Encoded Proteins
IDBP-182154
deafness, autosomal recessive 59 (human)
IDBP-535236
deafness, autosomal recessive 59 (human)
IDBP-532459
deafness, autosomal recessive 59 (human)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000204311:
The protein encoded by this gene is a member of the gasdermin family, a family which is found only in vertebrates. The encoded protein is required for the proper function of auditory pathway neurons. Defects in this gene are a cause of non-syndromic sensorineural deafness autosomal recessive type 59 (DFNB59). [provided by RefSeq, Dec 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:76648476-76658556
Strand Forward strand
Band C3
Transcripts
ENSMUST00000099986 ENSMUSP00000097566
ENSMUST00000153471 ENSMUSP00000114409
ENSMUST00000144817 ENSMUSP00000119264
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0007605 sensory perception of sound
Cellular Component
GO:0043025 neuronal cell body
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000204311
View Gene Order
ENSBTAG00000033254
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.330312 Mm.488660
RefSeq NM_001080711 XM_006499816 XM_006499817
OMIM
CCDS CCDS38153
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca