Version 5.4
Mus musculus Gene: Cgnl1
Summary
InnateDB Gene IDBG-183048.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cgnl1
Gene Name cingulin-like 1
Synonyms 4933421H10Rik; 9930020M10Rik; AI503810; Jacop
Species Mus musculus
Ensembl Gene ENSMUSG00000032232
Encoded Proteins
IDBP-183050
cingulin-like 1
IDBP-400684
cingulin-like 1
IDBP-400681
cingulin-like 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000128849:
This gene encodes a member of the cingulin family. The encoded protein localizes to both adherens and tight cell-cell junctions and mediates junction assembly and maintenance by regulating the activity of the small GTPases RhoA and Rac1. Heterozygous chromosomal rearrangements resulting in association of the promoter for this gene with the aromatase gene are a cause of aromatase excess syndrome. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Nov 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:71626509-71771602
Strand Reverse strand
Band D
Transcripts
ENSMUST00000072899 ENSMUSP00000072672
ENSMUST00000121322 ENSMUSP00000113917
ENSMUST00000122065 ENSMUSP00000112479
ENSMUST00000152224
ENSMUST00000136044
ENSMUST00000146567
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003774 motor activity
Biological Process
GO:0008150 biological_process
GO:0008152 metabolic process
Cellular Component
GO:0005923 tight junction
GO:0015629 actin cytoskeleton
GO:0016459 myosin complex
GO:0043296 apical junction complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000128849
View Gene Order
ENSBTAG00000008575
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.99961
RefSeq NM_026599 XM_006511394 XM_006511395
OMIM
CCDS CCDS23328
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca