InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Ppef1

Summary

InnateDB Gene

IDBG-183071.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ppef1

Gene Name

protein phosphatase with EF hand calcium-binding domain 1

Synonyms

Species

Mus musculus

Ensembl Gene

ENSMUSG00000062168

Encoded Proteins

IDBP-183073

protein phosphatase with EF hand calcium-binding domain 1

IDBP-532723

protein phosphatase with EF hand calcium-binding domain 1

IDBP-541815

protein phosphatase with EF hand calcium-binding domain 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000086717:
This gene encodes a member of the serine/threonine protein phosphatase with EF-hand motif family. The protein contains a protein phosphatase catalytic domain, and at least two EF-hand calcium-binding motifs in its C terminus. Although its substrate(s) is unknown, the encoded protein has been suggested to play a role in specific sensory neuron function and/or development. This gene shares high sequence similarity with the Drosophila retinal degeneration C (rdgC) gene. Several alternatively spliced transcript variants, each encoding a distinct isoform, have been described. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome X:160623094-160735765

Strand

Reverse strand

Band

Transcripts

ENSMUST00000071204	ENSMUSP00000071191
ENSMUST00000135856	ENSMUSP00000123408
ENSMUST00000136888	ENSMUSP00000121692

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004721	phosphoprotein phosphatase activity
GO:0004722	protein serine/threonine phosphatase activity
GO:0005506	iron ion binding
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0016787	hydrolase activity
GO:0030145	manganese ion binding