Version 5.4
Mus musculus Gene: Rhag
Summary
InnateDB Gene IDBG-183297.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rhag
Gene Name Rhesus blood group-associated A glycoprotein
Synonyms CD241; Rh50; Rh50A
Species Mus musculus
Ensembl Gene ENSMUSG00000023926
Encoded Proteins
IDBP-183299
Rhesus blood group-associated A glycoprotein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000112077:
The protein encoded by this gene is erythrocyte-specific and is thought to be part of a membrane channel that transports ammonium and carbon dioxide across the blood cell membrane. The encoded protein appears to interact with Rh blood group antigens and Rh30 polypeptides. Defects in this gene are a cause of regulator type Rh-null hemolytic anemia (RHN), or Rh-deficiency syndrome.[provided by RefSeq, Mar 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:40811126-40840754
Strand Forward strand
Band B2
Transcripts
ENSMUST00000024721 ENSMUSP00000024721
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 2 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008519 ammonium transmembrane transporter activity
GO:0030506 ankyrin binding
Biological Process
GO:0006873 cellular ion homeostasis
GO:0015670 carbon dioxide transport
GO:0015696 ammonium transport
GO:0048821 erythrocyte development
GO:0060586 multicellular organismal iron ion homeostasis
GO:0072488 ammonium transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000112077
View Gene Order
ENSBTAG00000011300
Not yet available
Pathways
NETPATH
REACTOME
REACT_217615
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
REACT_247550
SLC-mediated transmembrane transport pathway
REACT_188937
Metabolism pathway
REACT_198711
Rhesus glycoproteins mediate ammonium transport. pathway
REACT_199094
Erythrocytes take up carbon dioxide and release oxygen pathway
REACT_199095
O2/CO2 exchange in erythrocytes pathway
REACT_253400
Transmembrane transport of small molecules pathway
REACT_199098
Erythrocytes take up oxygen and release carbon dioxide pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_20508
Rhesus glycoproteins mediate ammonium transport. pathway
REACT_19305
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
REACT_121380
Erythrocytes take up oxygen and release carbon dioxide pathway
REACT_121329
Erythrocytes take up carbon dioxide and release oxygen pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_120969
O2/CO2 exchange in erythrocytes pathway
REACT_111217
Metabolism pathway
REACT_19118
SLC-mediated transmembrane transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.12961 Mm.472538
RefSeq NM_011269 XM_006523912
OMIM
CCDS CCDS28787
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca