Homo sapiens Gene: CD151 | |||||||||||||||||||||||
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Summary | |||||||||||||||||||||||
InnateDB Gene | IDBG-18403.6 | ||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
Gene Symbol | CD151 | ||||||||||||||||||||||
Gene Name | CD151 molecule (Raph blood group) | ||||||||||||||||||||||
Synonyms | GP27; MER2; PETA-3; RAPH; SFA1; TSPAN24 | ||||||||||||||||||||||
Species | Homo sapiens | ||||||||||||||||||||||
Ensembl Gene | ENSG00000177697 | ||||||||||||||||||||||
Encoded Proteins |
CD151 molecule (Raph blood group)
CD151 molecule (Raph blood group)
CD151 molecule (Raph blood group)
CD151 molecule (Raph blood group)
CD151 molecule (Raph blood group)
CD151 molecule (Raph blood group)
CD151 molecule (Raph blood group)
CD151 molecule (Raph blood group)
CD151 molecule (Raph blood group)
CD151 molecule (Raph blood group)
CD151 molecule (Raph blood group)
CD151 molecule (Raph blood group)
CD151 molecule (Raph blood group)
CD151 molecule (Raph blood group)
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Protein Structure | |||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
Summary |
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||
Genomic Location | Chromosome 11:832843-839831 | ||||||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||||||
Band | p15.5 | ||||||||||||||||||||||
Transcripts | |||||||||||||||||||||||
Interactions | |||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||
Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||||||||
NETPATH |
Alpha6Beta4Integrin pathway
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REACTOME |
Assembly of collagen fibrils and other multimeric structures pathway
Type I hemidesmosome assembly pathway
Cell-Cell communication pathway
Extracellular matrix organization pathway
Cell junction organization pathway
Collagen formation pathway
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KEGG | |||||||||||||||||||||||
INOH | |||||||||||||||||||||||
PID NCI | |||||||||||||||||||||||
Cross-References | |||||||||||||||||||||||
SwissProt | |||||||||||||||||||||||
TrEMBL | E9PK37 E9PP93 | ||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||
Entrez Gene | 977 | ||||||||||||||||||||||
UniGene | Hs.654379 | ||||||||||||||||||||||
RefSeq | NM_001039490 NM_004357 NM_139029 NM_139030 | ||||||||||||||||||||||
HUGO | HGNC:1630 | ||||||||||||||||||||||
OMIM | 602243 | ||||||||||||||||||||||
CCDS | CCDS7719 | ||||||||||||||||||||||
HPRD | 03763 | ||||||||||||||||||||||
IMGT | |||||||||||||||||||||||
EMBL | AP006621 AP006623 | ||||||||||||||||||||||
GenPept | |||||||||||||||||||||||
RNA Seq Atlas | 977 | ||||||||||||||||||||||