Homo sapiens Gene: SERPINA3 | |||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Summary | |||||||||||||||||||
InnateDB Gene | IDBG-18406.6 | ||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
Gene Symbol | SERPINA3 | ||||||||||||||||||
Gene Name | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | ||||||||||||||||||
Synonyms | |||||||||||||||||||
Species | Homo sapiens | ||||||||||||||||||
Ensembl Gene | ENSG00000196136 | ||||||||||||||||||
Encoded Proteins |
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
|
||||||||||||||||||
Protein Structure | |||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
Entrez Gene | |||||||||||||||||||
Summary |
The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease. [provided by RefSeq, Jul 2008] |
||||||||||||||||||
Gene Information | |||||||||||||||||||
Type | Protein coding | ||||||||||||||||||
Genomic Location | Chromosome 14:94612384-94624055 | ||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||
Band | q32.13 | ||||||||||||||||||
Transcripts | |||||||||||||||||||
Interactions | |||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
|
||||||||||||||||||
Gene Ontology | |||||||||||||||||||
Molecular Function |
|
||||||||||||||||||
Biological Process |
|
||||||||||||||||||
Cellular Component |
|
||||||||||||||||||
Orthologs | |||||||||||||||||||
No orthologs found for this gene | |||||||||||||||||||
Cross-References | |||||||||||||||||||
SwissProt | |||||||||||||||||||
TrEMBL | |||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||
Entrez Gene | |||||||||||||||||||
UniGene | Hs.534293 Hs.731935 | ||||||||||||||||||
RefSeq | NM_001085 | ||||||||||||||||||
HUGO | |||||||||||||||||||
OMIM | |||||||||||||||||||
CCDS | CCDS32150 | ||||||||||||||||||
HPRD | 00120 | ||||||||||||||||||
IMGT | |||||||||||||||||||
EMBL | |||||||||||||||||||
GenPept | |||||||||||||||||||
RNA Seq Atlas | |||||||||||||||||||