Version 5.4
| Mus musculus Gene: Car11 | |||||||
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| Summary | |||||||
| InnateDB Gene | IDBG-184102.6 | ||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
| Gene Symbol | Car11 | ||||||
| Gene Name | carbonic anhydrase 11 | ||||||
| Synonyms | Ca11 | ||||||
| Species | Mus musculus | ||||||
| Ensembl Gene | ENSMUSG00000003273 | ||||||
| Encoded Proteins |
carbonic anhydrase 11
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||
| Entrez Gene | |||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000063180:
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA XI is likely a secreted protein, however, radical changes at active site residues completely conserved in CA isozymes with catalytic activity, make it unlikely that it has carbonic anhydrase activity. It shares properties in common with two other acatalytic CA isoforms, CA VIII and CA X. CA XI is most abundantly expressed in brain, and may play a general role in the central nervous system. [provided by RefSeq, Jul 2008] Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA XI is likely a secreted protein, however, radical changes at active site residues completely conserved in CA isozymes with catalytic activity, make it unlikely that it has carbonic anhydrase activity. It shares properties in common with two other acatalytic CA isoforms, CA VIII and CA X. CA XI is most abundantly expressed in brain, and may play a general role in the central nervous system. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||
| Type | Protein coding | ||||||
| Genomic Location | Chromosome 7:45699843-45704682 | ||||||
| Strand | Forward strand | ||||||
| Band | B3 | ||||||
| Transcripts |
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| Interactions | |||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Cross-References | |||||||
| SwissProt | O70354 | ||||||
| TrEMBL | Q541E9 | ||||||
| UniProt Splice Variant | |||||||
| Entrez Gene | 12348 | ||||||
| UniGene | Mm.27736 | ||||||
| RefSeq | NM_009800 | ||||||
| OMIM | |||||||
| CCDS | CCDS21259 | ||||||
| HPRD | |||||||
| IMGT | |||||||
| MGI ID | MGI:1336193 | ||||||
| MGI Symbol | Car11 | ||||||
| EMBL | AB079601 AF050105 AY075026 BC019393 CH466603 | ||||||
| GenPept | AAD08801 AAH19393 AAL78174 BAC07262 EDL22885 | ||||||
| RNA Seq Atlas | 12348 | ||||||