Version 5.4
| Mus musculus Gene: Mrps18a | |||||||||||||
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| Summary | |||||||||||||
| InnateDB Gene | IDBG-185943.6 | ||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
| Gene Symbol | Mrps18a | ||||||||||||
| Gene Name | mitochondrial ribosomal protein S18A | ||||||||||||
| Synonyms | 1110004O20Rik; C79712 | ||||||||||||
| Species | Mus musculus | ||||||||||||
| Ensembl Gene | ENSMUSG00000023967 | ||||||||||||
| Encoded Proteins |
mitochondrial ribosomal protein S18A
mitochondrial ribosomal protein S18A
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| Protein Structure | |||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||
| Entrez Gene | |||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000096080:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondrial S18 proteins are no more closely related to each other than they are to the prokaryotic S18 proteins. A pseudogene corresponding to this gene is found on chromosome 3p. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jul 2010] |
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| Gene Information | |||||||||||||
| Type | Protein coding | ||||||||||||
| Genomic Location | Chromosome 17:46110986-46128910 | ||||||||||||
| Strand | Forward strand | ||||||||||||
| Band | C | ||||||||||||
| Transcripts |
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| Interactions | |||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||||||
| NETPATH | |||||||||||||
| REACTOME | |||||||||||||
| KEGG |
Ribosome pathway
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| INOH | |||||||||||||
| PID NCI | |||||||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||||||
| NETPATH | |||||||||||||
| REACTOME |
Organelle biogenesis and maintenance pathway
Mitochondrial translation pathway
Mitochondrial translation initiation pathway
Mitochondrial translation termination pathway
Mitochondrial translation elongation pathway
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| KEGG |
Ribosome pathway
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| INOH | |||||||||||||
| PID NCI | |||||||||||||
| Cross-References | |||||||||||||
| SwissProt | |||||||||||||
| TrEMBL | D3Z603 Q5U5I3 | ||||||||||||
| UniProt Splice Variant | |||||||||||||
| Entrez Gene | 68565 | ||||||||||||
| UniGene | Mm.287443 | ||||||||||||
| RefSeq | NM_026768 | ||||||||||||
| OMIM | |||||||||||||
| CCDS | CCDS28819 | ||||||||||||
| HPRD | |||||||||||||
| IMGT | |||||||||||||
| MGI ID | MGI:1915815 | ||||||||||||
| MGI Symbol | Mrps18a | ||||||||||||
| EMBL | AC110562 AK028226 AK172171 BC058959 CH466559 | ||||||||||||
| GenPept | AAH58959 BAC25825 BAE42864 EDL23468 EDL23471 | ||||||||||||
| RNA Seq Atlas | 68565 | ||||||||||||