Mus musculus Gene: Krt86
Summary
InnateDB Gene IDBG-185990.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Krt86
Gene Name keratin 86
Synonyms 5430421N21Rik; AI325212; Khb4; Krt2-10; Krt2-11; MHb4
Species Mus musculus
Ensembl Gene ENSMUSG00000067614
Encoded Proteins
keratin 86
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000170442:
The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB1 and KRTHB3, is found primarily in the hair cortex. Mutations in this gene and KRTHB1 have been observed in patients with a rare dominant hair disease, monilethrix. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:101473478-101479983
Strand Forward strand
Band F2
Transcripts
ENSMUST00000088049 ENSMUSP00000085365
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005198 structural molecule activity
Biological Process
Cellular Component
GO:0005882 intermediate filament
GO:0045095 keratin filament
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt P97861
TrEMBL B2RTB6 Q3TUZ8
UniProt Splice Variant
Entrez Gene 16679
UniGene Mm.383183
RefSeq NM_010667
OMIM
CCDS CCDS37218
HPRD
IMGT
MGI ID MGI:109362
MGI Symbol Krt86
EMBL AK160496 AK161149 BC139222 CH466550 X99143
GenPept AAI39223 BAE35823 BAE36215 CAA67580 EDL04042
RNA Seq Atlas 16679