Version 5.4
Mus musculus Gene: Nol3
Summary
InnateDB Gene IDBG-187078.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nol3
Gene Name nucleolar protein 3 (apoptosis repressor with CARD domain)
Synonyms ARC; B430311C09Rik; MYC; NOP; Nop30
Species Mus musculus
Ensembl Gene ENSMUSG00000014776
Encoded Proteins
IDBP-187080
nucleolar protein 3 (apoptosis repressor with CARD domain)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000140939:
This gene encodes an anti-apoptotic protein that has been shown to down-regulate the enzyme activities of caspase 2, caspase 8 and tumor protein p53. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:105276447-105281939
Strand Forward strand
Band D3
Transcripts
ENSMUST00000014920 ENSMUSP00000014920
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 23 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 23 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0042802 identical protein binding
Biological Process
GO:0001666 response to hypoxia
GO:0006397 mRNA processing
GO:0008380 RNA splicing
GO:0010468 regulation of gene expression
GO:0014876 response to injury involved in regulation of muscle adaptation
GO:0042981 regulation of apoptotic process
Cellular Component
GO:0005622 intracellular
GO:0005730 nucleolus
GO:0005739 mitochondrion
GO:0016528 sarcoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000140939
View Gene Order
ENSBTAG00000003519
Not yet available
Cross-References
SwissProt Q9D1X0
TrEMBL Q53YU5
UniProt Splice Variant
Entrez Gene 78688
UniGene Mm.475715
RefSeq NM_030152 XM_006531503
OMIM
CCDS CCDS52657
HPRD
IMGT
MGI ID MGI:1925938
MGI Symbol Nol3
EMBL AK021023 AK053846 AY459322 CH466525
GenPept AAR22550 BAB32281 BAC35554 EDL11261
RNA Seq Atlas 78688

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca