Version 5.4
Mus musculus Gene: Klhdc3
Summary
InnateDB Gene IDBG-187891.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Klhdc3
Gene Name kelch domain containing 3
Synonyms 1300011D16Rik; Peas
Species Mus musculus
Ensembl Gene ENSMUSG00000063576
Encoded Proteins
IDBP-187893
kelch domain containing 3
IDBP-624588
kelch domain containing 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000124702:
The protein encoded by this gene contains six repeated kelch motifs that are structurally similar to recombination activating gene 2, a protein involved in the activation of the V(D)J recombination. In mouse, this gene is found to be expressed specifically in testis. Its expression in pachytene spermatocytes is localized to cytoplasma and meiotic chromatin, suggesting that this gene may be involved in meiotic recombination. [provided by RefSeq, Jun 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:46674550-46680930
Strand Reverse strand
Band C
Transcripts
ENSMUST00000071841 ENSMUSP00000071743
ENSMUST00000165007 ENSMUSP00000128271
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003682 chromatin binding
GO:0005515 protein binding
Biological Process
GO:0007126 meiotic nuclear division
GO:0008150 biological_process
Cellular Component
GO:0000790 nuclear chromatin
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000124702
View Gene Order
ENSBTAG00000012746
Not yet available
Pathways
NETPATH
REACTOME
REACT_239697
Unfolded Protein Response (UPR) pathway
REACT_247926
Metabolism of proteins pathway
REACT_231085
IRE1alpha activates chaperones pathway
REACT_106572
XBP1(S) activates chaperone genes pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_18273
XBP1(S) activates chaperone genes pathway
REACT_18368
IRE1alpha activates chaperones pathway
REACT_18356
Unfolded Protein Response (UPR) pathway
REACT_17015
Metabolism of proteins pathway
REACT_218371
IRE1alpha activates chaperones pathway
REACT_213782
Metabolism of proteins pathway
REACT_211201
XBP1(S) activates chaperone genes pathway
REACT_226614
Unfolded Protein Response (UPR) pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q8VEM9
TrEMBL
UniProt Splice Variant
Entrez Gene 71765
UniGene Mm.254784
RefSeq NM_001163729 NM_027910 XM_006524943
OMIM
CCDS CCDS28834
HPRD
IMGT
MGI ID MGI:2651568
MGI Symbol Klhdc3
EMBL AB053465 AB074009 AJ278127 AK004964 AK141673 AK170623 BC018154
GenPept AAH18154 BAB23704 BAB62016 BAB91441 BAE24793 BAE41917 CAC34582
RNA Seq Atlas 71765

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca