Version 5.4
Mus musculus Gene: Tbcc
Summary
InnateDB Gene IDBG-188505.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tbcc
Gene Name tubulin-specific chaperone C
Synonyms 2810055C19Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000036430
Encoded Proteins
IDBP-188507
tubulin-specific chaperone C
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000124659:
Cofactor C is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:46890621-46892463
Strand Forward strand
Band C
Transcripts
ENSMUST00000040434 ENSMUSP00000048696
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
Biological Process
GO:0000902 cell morphogenesis
GO:0006184 GTP catabolic process
GO:0007023 post-chaperonin tubulin folding pathway
Cellular Component
GO:0005737 cytoplasm
GO:0032391 photoreceptor connecting cilium
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000124659
View Gene Order
ENSBTAG00000000940
Not yet available
Pathways
NETPATH
REACTOME
REACT_247926
Metabolism of proteins pathway
REACT_247933
Post-chaperonin tubulin folding pathway pathway
REACT_245534
Protein folding pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_16967
Post-chaperonin tubulin folding pathway pathway
REACT_16952
Protein folding pathway
REACT_17015
Metabolism of proteins pathway
REACT_215959
Post-chaperonin tubulin folding pathway pathway
REACT_213782
Metabolism of proteins pathway
REACT_215927
Protein folding pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.33780
RefSeq NM_178385
OMIM
CCDS CCDS28843
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca