Version 5.4
Mus musculus Gene: Siglech
Summary
InnateDB Gene IDBG-188669.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Siglech
Gene Name sialic acid binding Ig-like lectin H
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000051504
Encoded Proteins
IDBP-188671
sialic acid binding Ig-like lectin H
IDBP-188673
sialic acid binding Ig-like lectin H
IDBP-400626
sialic acid binding Ig-like lectin H
IDBP-534966
sialic acid binding Ig-like lectin H
IDBP-625333
sialic acid binding Ig-like lectin H
IDBP-625344
sialic acid binding Ig-like lectin H
IDBP-625346
sialic acid binding Ig-like lectin H
IDBP-625349
sialic acid binding Ig-like lectin H
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation
Summary
PMID 21208791
Siglech is a member of the SIGLEC protein family that recognize sialoside-based patterns and plays a role in the attenuation of innate immunity to avoid autoimmune destruction.
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 7:55768178-55778925
Strand Forward strand
Band B5
Transcripts
ENSMUST00000060416 ENSMUSP00000058875
ENSMUST00000094360 ENSMUSP00000091920
ENSMUST00000121492 ENSMUSP00000113665
ENSMUST00000154933 ENSMUSP00000122697
ENSMUST00000172988 ENSMUSP00000134017
ENSMUST00000165045 ENSMUSP00000130632
ENSMUST00000173835 ENSMUSP00000134721
ENSMUST00000171077 ENSMUSP00000130943
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0016021 integral component of membrane
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
KEGG
mmu04640
Hematopoietic cell lineage pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.44425
RefSeq NM_178706 XM_006540827 XM_006540829 XM_006540831 XM_006540833
OMIM
CCDS CCDS21313
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca