Version 5.4
Mus musculus Gene: Acrbp
Summary
InnateDB Gene IDBG-188950.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Acrbp
Gene Name proacrosin binding protein
Synonyms OY-TES-1; sp32
Species Mus musculus
Ensembl Gene ENSMUSG00000072770
Encoded Proteins
IDBP-188952
proacrosin binding protein
IDBP-188954
proacrosin binding protein
IDBP-256077
proacrosin binding protein
IDBP-256079
proacrosin binding protein
IDBP-256081
proacrosin binding protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000111644:
The protein encoded by this gene is similar to proacrosin binding protein sp32 precursor found in mouse, guinea pig, and pig. This protein is located in the sperm acrosome and is thought to function as a binding protein to proacrosin for packaging and condensation of the acrosin zymogen in the acrosomal matrix. This protein is a member of the cancer/testis family of antigens and it is found to be immunogenic. In normal tissues, this mRNA is expressed only in testis, whereas it is detected in a range of different tumor types such as bladder, breast, lung, liver, and colon. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:125049689-125063267
Strand Forward strand
Band F2
Transcripts
ENSMUST00000032481 ENSMUSP00000032481
ENSMUST00000088294 ENSMUSP00000085632
ENSMUST00000112414 ENSMUSP00000108033
ENSMUST00000112413 ENSMUSP00000108032
ENSMUST00000112412 ENSMUSP00000108031
ENSMUST00000124159
ENSMUST00000136100
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016504 peptidase activator activity
Biological Process
GO:0007286 spermatid development
GO:0010952 positive regulation of peptidase activity
Cellular Component
GO:0001669 acrosomal vesicle
GO:0005576 extracellular region
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000111644
View Gene Order
ENSBTAG00000034246
Not yet available
Cross-References
SwissProt
TrEMBL F2Z440
UniProt Splice Variant
Entrez Gene 54137
UniGene Mm.347910
RefSeq NM_001127340 NM_016845
OMIM
CCDS CCDS20542 CCDS51910
HPRD
IMGT
MGI ID MGI:1859515
MGI Symbol Acrbp
EMBL AC134529
GenPept
RNA Seq Atlas 54137

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca