Version 5.4
| Mus musculus Gene: Dph5 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-189756.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Dph5 | ||||||||
| Gene Name | DPH5 homolog (S. cerevisiae) | ||||||||
| Synonyms | 2410012M04Rik; AU045680; C80186 | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000033554 | ||||||||
| Encoded Proteins |
DPH5 homolog (S. cerevisiae)
DPH5 homolog (S. cerevisiae)
DPH5 homolog (S. cerevisiae)
DPH5 homolog (S. cerevisiae)
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000117543:
This gene encodes a component of the diphthamide synthesis pathway. Diphthamide is a post-translationally modified histidine residue found only on translation elongation factor 2. It is conserved from archaebacteria to humans, and is targeted by diphtheria toxin and Pseudomonas exotoxin A to halt cellular protein synthesis. The yeast and Chinese hamster homologs of this protein catalyze the trimethylation of the histidine residue on elongation factor 2, resulting in a diphthine moiety that is subsequently amidated to yield diphthamide. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 3:115887837-115934361 | ||||||||
| Strand | Forward strand | ||||||||
| Band | G1 | ||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | |||||||||
| UniGene | Mm.5915 | ||||||||
| RefSeq | NM_027193 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS17782 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| MGI ID | |||||||||
| MGI Symbol | |||||||||
| EMBL | |||||||||
| GenPept | |||||||||
| RNA Seq Atlas | |||||||||