Version 5.4
Mus musculus Gene: Kcna6
Summary
InnateDB Gene IDBG-190251.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Kcna6
Gene Name potassium voltage-gated channel, shaker-related, subfamily, member 6
Synonyms Kv1.6; MK1.6
Species Mus musculus
Ensembl Gene ENSMUSG00000038077
Encoded Proteins
IDBP-190253
potassium voltage-gated channel, shaker-related, subfamily, member 6
IDBP-256425
potassium voltage-gated channel, shaker-related, subfamily, member 6
IDBP-789769
potassium voltage-gated channel, shaker-related, subfamily, member 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000151079:
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class. The coding region of this gene is intronless, and the gene is clustered with genes KCNA1 and KCNA5 on chromosome 12. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:126708329-126740674
Strand Reverse strand
Band F3
Transcripts
ENSMUST00000040751 ENSMUSP00000036872
ENSMUST00000112242 ENSMUSP00000107861
ENSMUST00000128137
ENSMUST00000185333 ENSMUSP00000139481
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005216 ion channel activity
GO:0005251 delayed rectifier potassium channel activity
GO:0005515 protein binding
Biological Process
GO:0006811 ion transport
GO:0034765 regulation of ion transmembrane transport
GO:0051260 protein homooligomerization
GO:0055085 transmembrane transport
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0008076 voltage-gated potassium channel complex
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000151079
View Gene Order
ENSBTAG00000047191
Not yet available
Pathways
NETPATH
REACTOME
REACT_202800
Potassium Channels pathway
REACT_259290
Neuronal System pathway
REACT_199077
Voltage gated Potassium channels pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_75770
Voltage gated Potassium channels pathway
REACT_13685
Neuronal System pathway
REACT_75908
Potassium Channels pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 16494
UniGene
RefSeq NM_013568 XM_006505638 XM_006505639
OMIM
CCDS CCDS20556
HPRD
IMGT
MGI ID MGI:96663
MGI Symbol Kcna6
EMBL BC048782 BC054804 M96688
GenPept AAA39772 AAH48782 AAH54804
RNA Seq Atlas 16494

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca