Mus musculus Gene: Il20
Summary
InnateDB Gene IDBG-190611.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Il20
Gene Name interleukin 20
Synonyms Zcyto10
Species Mus musculus
Ensembl Gene ENSMUSG00000026416
Encoded Proteins
interleukin 20
interleukin 20
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000162891:
The protein encoded by this gene is a cytokine structurally related to interleukin 10 (IL10). This cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this cytokine is found to be expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:130906985-130911451
Strand Reverse strand
Band E4
Transcripts
ENSMUST00000027673 ENSMUSP00000027673
ENSMUST00000188581 ENSMUSP00000141088
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005125 cytokine activity
GO:0045517 interleukin-20 receptor binding
GO:0045518 interleukin-22 receptor binding
Biological Process
GO:0007262 STAT protein import into nucleus
GO:0030097 hemopoiesis
GO:0045672 positive regulation of osteoclast differentiation
Cellular Component
GO:0005615 extracellular space
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
KEGG
Cytokine-cytokine receptor interaction pathway
Jak-STAT signaling pathway pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
Cytokine-cytokine receptor interaction pathway
Jak-STAT signaling pathway pathway
INOH
PID NCI
Cross-References
SwissProt Q9JKV9
TrEMBL Q2NKI0 Q2THG5
UniProt Splice Variant
Entrez Gene 58181
UniGene Mm.103794
RefSeq NM_021380 XM_006529765
OMIM
CCDS CCDS15263
HPRD
IMGT
MGI ID MGI:1890473
MGI Symbol Il20
EMBL AF224267 AY876923 BC111821 CH466520
GenPept AAF36680 AAI11822 AAW78349 EDL39725
RNA Seq Atlas 58181