InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Rab5a

Summary

InnateDB Gene

IDBG-190768.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Rab5a

Gene Name

RAB5A, member RAS oncogene family

Synonyms

Species

Mus musculus

Ensembl Gene

ENSMUSG00000017831

Encoded Proteins

IDBP-190770

RAB5A, member RAS oncogene family

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000144566:

Gene Information

Type

Protein coding

Genomic Location

Chromosome 17:53479234-53507671

Strand

Forward strand

Band

Transcripts

ENSMUST00000017975

ENSMUSP00000017975

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 63 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	63 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003924	GTPase activity
GO:0005515	protein binding
GO:0005525	GTP binding
GO:0019001	guanyl nucleotide binding
GO:0019003	GDP binding
GO:0051021	GDP-dissociation inhibitor binding

Biological Process

GO:0006184	GTP catabolic process
GO:0006886	intracellular protein transport
GO:0006897	endocytosis
GO:0006913	nucleocytoplasmic transport
GO:0007165	signal transduction
GO:0007264	small GTPase mediated signal transduction
GO:0007399	nervous system development
GO:0014911	positive regulation of smooth muscle cell migration
GO:0015031	protein transport
GO:0030154	cell differentiation
GO:0045921	positive regulation of exocytosis
GO:0048169	regulation of long-term neuronal synaptic plasticity
GO:0048661	positive regulation of smooth muscle cell proliferation
GO:0051489	regulation of filopodium assembly
GO:2000286	receptor internalization involved in canonical Wnt receptor signaling pathway

Cellular Component

GO:0001726	ruffle
GO:0005622	intracellular
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005768	endosome
GO:0005769	early endosome
GO:0005829	cytosol
GO:0005886	plasma membrane
GO:0008021	synaptic vesicle
GO:0015629	actin cytoskeleton
GO:0016020	membrane
GO:0030139	endocytic vesicle
GO:0030424	axon
GO:0030425	dendrite
GO:0031901	early endosome membrane
GO:0042470	melanosome
GO:0042589	zymogen granule membrane
GO:0043005	neuron projection
GO:0043025	neuronal cell body
GO:0043195	terminal bouton
GO:0043234	protein complex
GO:0045121	membrane raft
GO:0045335	phagocytic vesicle
GO:0048471	perinuclear region of cytoplasm
GO:0055037	recycling endosome
GO:0070062	extracellular vesicular exosome