Version 5.4
Mus musculus Gene: Tpst2
Summary
InnateDB Gene IDBG-191044.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tpst2
Gene Name protein-tyrosine sulfotransferase 2
Synonyms AI448750; D5Ucla3; grm; grt; Tango13b
Species Mus musculus
Ensembl Gene ENSMUSG00000029344
Encoded Proteins
IDBP-191046
protein-tyrosine sulfotransferase 2
IDBP-191048
protein-tyrosine sulfotransferase 2
IDBP-536811
protein-tyrosine sulfotransferase 2
IDBP-539202
protein-tyrosine sulfotransferase 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000128294:
The protein encoded by this gene catalyzes the O-sulfation of tyrosine residues within acidic regions of proteins. The encoded protein is a type II integral membrane protein found in the Golgi body. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:112276691-112315361
Strand Forward strand
Band F
Transcripts
ENSMUST00000071455 ENSMUSP00000071399
ENSMUST00000031287 ENSMUSP00000031287
ENSMUST00000134071
ENSMUST00000151947 ENSMUSP00000114592
ENSMUST00000140262 ENSMUSP00000116816
ENSMUST00000139482
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008146 sulfotransferase activity
GO:0008476 protein-tyrosine sulfotransferase activity
Biological Process
GO:0006478 peptidyl-tyrosine sulfation
GO:0007342 fusion of sperm to egg plasma membrane
GO:0060468 prevention of polyspermy
Cellular Component
GO:0000139 Golgi membrane
GO:0005783 endoplasmic reticulum
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000128294
View Gene Order
ENSBTAG00000010368
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.250631 Mm.410089
RefSeq NM_009419 XM_006534847 XM_006534848 XM_006534849 XM_006534850
OMIM
CCDS CCDS19538
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca