Homo sapiens Gene: SEMA6B
Summary
InnateDB Gene IDBG-19110.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SEMA6B
Gene Name sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
Synonyms SEM-SEMA-Y; SEMA-VIB; SEMAN; semaZ
Species Homo sapiens
Ensembl Gene ENSG00000167680
Encoded Proteins
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the semaphorin family, a group of proteins characterized by the presence of a conserved semaphorin (sema) domain. Whereas some semaphorins are transmembrane proteins, others are secreted. Semaphorins play a major role in axon guidance. The protein encoded by this gene may be involved in both peripheral and central nervous system development. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:4542593-4559808
Strand Reverse strand
Band p13.3
Transcripts
ENST00000586582 ENSP00000467290
ENST00000586965 ENSP00000465722
ENST00000589889
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
GO:0005515 protein binding
GO:0030215 semaphorin receptor binding
Biological Process
GO:0007275 multicellular organismal development
GO:0007399 nervous system development
GO:0030154 cell differentiation
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
KEGG
Axon guidance pathway
INOH
PID NCI
Cross-References
SwissProt Q9H3T3
TrEMBL
UniProt Splice Variant
Entrez Gene 10501
UniGene Hs.465642
RefSeq NM_032108
HUGO HGNC:10739
OMIM 608873
CCDS CCDS12131
HPRD 12322
IMGT
EMBL AB022433 AC011498 AF216389 AY358939 BC142617 CH471139 FR839673
GenPept AAF87661 AAI42618 AAQ89298 BAB20669 CCA61013 EAW69208
RNA Seq Atlas 10501