Version 5.4
Mus musculus Gene: Chaf1a
Summary
InnateDB Gene IDBG-191494.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Chaf1a
Gene Name chromatin assembly factor 1, subunit A (p150)
Synonyms AL023013; AL024058; Cac1p; CAF-1
Species Mus musculus
Ensembl Gene ENSMUSG00000002835
Encoded Proteins
IDBP-191496
chromatin assembly factor 1, subunit A (p150)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000167670:
Chromatin assembly factor I (CAF1) is a nuclear complex consisting of p50, p60 (CHAF1B; MIM 601245), and p150 (CHAF1A) subunits that assembles histone octamers onto replicating DNA in vitro (Kaufman et al., 1995 [PubMed 7600578]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:56040416-56068026
Strand Forward strand
Band D
Transcripts
ENSMUST00000002914 ENSMUSP00000002914
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 58 interaction(s) predicted by orthology.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 58 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0042802 identical protein binding
GO:0070087 chromo shadow domain binding
Biological Process
GO:0006260 DNA replication
GO:0006281 DNA repair
GO:0006335 DNA replication-dependent nucleosome assembly
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007049 cell cycle
GO:0031497 chromatin assembly
Cellular Component
GO:0000790 nuclear chromatin
GO:0033186 CAF-1 complex
GO:0043234 protein complex
GO:0071778 WINAC complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000167670
View Gene Order
ENSBTAG00000008181
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt Q9QWF0
TrEMBL
UniProt Splice Variant
Entrez Gene 27221
UniGene
RefSeq NM_013733
OMIM
CCDS CCDS28892
HPRD
IMGT
MGI ID MGI:1351331
MGI Symbol Chaf1a
EMBL AJ132771 AK034839 AK161016 BC053740 CH466559
GenPept AAH53740 BAC28848 BAE36149 CAB55497 EDL23708
RNA Seq Atlas 27221

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca