Version 5.4
Mus musculus Gene: Klhdc8a
Summary
InnateDB Gene IDBG-191840.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Klhdc8a
Gene Name kelch domain containing 8A
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000042115
Encoded Proteins
IDBP-191842
kelch domain containing 8A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000162873:
This gene encodes a kelch domain-containing protein which is upregulated in cancer. Upregulated expression of the encoded protein may provide an alternative pathway for tumors to maintain aggressiveness in the absence of epidermal growth factor receptor dependence. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:132298626-132307357
Strand Forward strand
Band E4
Transcripts
ENSMUST00000046071 ENSMUSP00000038297
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000162873
View Gene Order
ENSBTAG00000015197
Not yet available
Cross-References
SwissProt Q91XA8
TrEMBL Q8C939 Q8R577
UniProt Splice Variant
Entrez Gene 213417
UniGene Mm.39723
RefSeq NM_144810 XM_006529354
OMIM
CCDS CCDS35706
HPRD
IMGT
MGI ID MGI:2442630
MGI Symbol Klhdc8a
EMBL AK043039 AK044318 AK080356 BC011135 BC023173
GenPept AAH11135 AAH23173 BAC31445 BAC31864 BAC37888
RNA Seq Atlas 213417

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca