Version 5.4
Mus musculus Gene: Phf21a
Summary
InnateDB Gene IDBG-192007.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Phf21a
Gene Name PHD finger protein 21A
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000058318
Encoded Proteins
IDBP-192009
PHD finger protein 21A
IDBP-192011
PHD finger protein 21A
IDBP-192013
PHD finger protein 21A
IDBP-258429
PHD finger protein 21A
IDBP-258431
PHD finger protein 21A
IDBP-258433
PHD finger protein 21A
IDBP-258435
PHD finger protein 21A
IDBP-258437
PHD finger protein 21A
IDBP-258439
PHD finger protein 21A
IDBP-535212
PHD finger protein 21A
IDBP-538985
PHD finger protein 21A
IDBP-534953
PHD finger protein 21A
IDBP-538131
PHD finger protein 21A
IDBP-534503
PHD finger protein 21A
IDBP-533383
PHD finger protein 21A
IDBP-535473
PHD finger protein 21A
IDBP-534152
PHD finger protein 21A
IDBP-536625
PHD finger protein 21A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000135365:
The PHF21A gene encodes BHC80, a component of a BRAF35 (MIM 605535)/histone deacetylase (HDAC; see MIM 601241) complex (BHC) that mediates repression of neuron-specific genes through the cis-regulatory element known as repressor element-1 (RE1) or neural restrictive silencer (NRS) (Hakimi et al., 2002 [PubMed 12032298]).[supplied by OMIM, Nov 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:92093117-92364666
Strand Forward strand
Band E1
Transcripts
ENSMUST00000090586 ENSMUSP00000088074
ENSMUST00000044036 ENSMUSP00000038497
ENSMUST00000068702 ENSMUSP00000070649
ENSMUST00000111297 ENSMUSP00000106928
ENSMUST00000111294 ENSMUSP00000106925
ENSMUST00000111293 ENSMUSP00000106924
ENSMUST00000111292 ENSMUSP00000106923
ENSMUST00000111291 ENSMUSP00000106922
ENSMUST00000111290 ENSMUSP00000106921
ENSMUST00000142528
ENSMUST00000162146 ENSMUSP00000124032
ENSMUST00000160235
ENSMUST00000162497 ENSMUSP00000124224
ENSMUST00000162188 ENSMUSP00000125628
ENSMUST00000128781 ENSMUSP00000125228
ENSMUST00000138995 ENSMUSP00000125734
ENSMUST00000159366 ENSMUSP00000124238
ENSMUST00000159961 ENSMUSP00000123955
ENSMUST00000159727 ENSMUSP00000124845
ENSMUST00000161067 ENSMUSP00000124255
ENSMUST00000161044
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001967 suckling behavior
Cellular Component
GO:0000118 histone deacetylase complex
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000135365
View Gene Order
ENSBTAG00000009611
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_24970
Factors involved in megakaryocyte development and platelet production pathway
REACT_228222
HDACs deacetylate histones pathway
REACT_172623
Chromatin organization pathway
REACT_172633
Chromatin modifying enzymes pathway
REACT_604
Hemostasis pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL A2AHG3 E0CZ79
UniProt Splice Variant
Entrez Gene 192285
UniGene Mm.330408
RefSeq NM_138755 NM_001109690 NM_001109691 XM_006498959 XM_006498960 XM_006498961 XM_006498962 XM_006498963 XM_006498964 XM_006498965 XM_006498966 XM_006498967 XM_006498968 XM_006498969 XM_006498970 XM_006498971 XM_006498972 XM_006498973 XM_006498974 XM_006498975 XM_006498976 XM_006498977 XM_006498978 XM_006498979 XM_006498980
OMIM
CCDS CCDS16442 CCDS50644 CCDS50645
HPRD
IMGT
MGI ID MGI:2384756
MGI Symbol Phf21a
EMBL AL691462 AL731709 AL732484
GenPept
RNA Seq Atlas 192285

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca