Version 5.4
| Mus musculus Gene: Klrd1 | |||||||||||
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| Summary | |||||||||||
| InnateDB Gene | IDBG-192118.6 | ||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
| Gene Symbol | Klrd1 | ||||||||||
| Gene Name | killer cell lectin-like receptor, subfamily D, member 1 | ||||||||||
| Synonyms | CD94 | ||||||||||
| Species | Mus musculus | ||||||||||
| Ensembl Gene | ENSMUSG00000030165 | ||||||||||
| Encoded Proteins |
killer cell lectin-like receptor, subfamily D, member 1
killer cell lectin-like receptor, subfamily D, member 1
killer cell lectin-like receptor, subfamily D, member 1
killer cell lectin-like receptor, subfamily D, member 1
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||
| Entrez Gene | |||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000134539:
Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||
| Type | Protein coding | ||||||||||
| Genomic Location | Chromosome 6:129591782-129598775 | ||||||||||
| Strand | Forward strand | ||||||||||
| Band | F3 | ||||||||||
| Transcripts |
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| Interactions | |||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||
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Species
Homo sapiens
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Gene ID
Gene Order
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| Pathways | |||||||||||
| NETPATH | |||||||||||
| REACTOME |
Innate Immune System pathway
Immune System pathway
DAP12 interactions pathway
DAP12 signaling pathway
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| KEGG |
Antigen processing and presentation pathway
Natural killer cell mediated cytotoxicity pathway
Graft-versus-host disease pathway
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| INOH | |||||||||||
| PID NCI | |||||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||||
| NETPATH | |||||||||||
| REACTOME |
DAP12 signaling pathway
DAP12 interactions pathway
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell pathway
Innate Immune System pathway
Adaptive Immune System pathway
Immune System pathway
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| KEGG |
Antigen processing and presentation pathway
Natural killer cell mediated cytotoxicity pathway
Graft-versus-host disease pathway
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| INOH | |||||||||||
| PID NCI | |||||||||||
| Cross-References | |||||||||||
| SwissProt | O54707 | ||||||||||
| TrEMBL | D3Z626 E0CZ14 E9Q3T9 | ||||||||||
| UniProt Splice Variant | |||||||||||
| Entrez Gene | 16643 | ||||||||||
| UniGene | Mm.391515 | ||||||||||
| RefSeq | NM_010654 XM_006505655 | ||||||||||
| OMIM | |||||||||||
| CCDS | CCDS57456 | ||||||||||
| HPRD | |||||||||||
| IMGT | |||||||||||
| MGI ID | MGI:1196275 | ||||||||||
| MGI Symbol | Klrd1 | ||||||||||
| EMBL | AC161602 AC171002 AF030311 AF030312 AF039025 AF057714 AK136548 BC117112 BC120854 CH466523 | ||||||||||
| GenPept | AAC28243 AAC28244 AAC33713 AAD02116 AAI17113 AAI20855 BAE23039 EDK99936 | ||||||||||
| RNA Seq Atlas | 16643 | ||||||||||