Mus musculus Gene: Mrps22
Summary
InnateDB Gene IDBG-192484.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mrps22
Gene Name mitochondrial ribosomal protein S22
Synonyms 3100002P07Rik; Rpms22
Species Mus musculus
Ensembl Gene ENSMUSG00000032459
Encoded Proteins
mitochondrial ribosomal protein S22
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000175110:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that does not seem to have a counterpart in prokaryotic and fungal-mitochondrial ribosomes. This gene lies telomeric of and is transcribed in the opposite direction from the forkhead box L2 gene. A pseudogene corresponding to this gene is found on chromosome Xq. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:98588730-98601660
Strand Reverse strand
Band E3.3
Transcripts
ENSMUST00000035034 ENSMUSP00000035034
ENSMUST00000190150
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 20 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003735 structural constituent of ribosome
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005739 mitochondrion
GO:0005763 mitochondrial small ribosomal subunit
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Mitochondrial translation pathway
Organelle biogenesis and maintenance pathway
Mitochondrial translation elongation pathway
Mitochondrial translation initiation pathway
Mitochondrial translation termination pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Organelle biogenesis and maintenance pathway
Mitochondrial translation pathway
Mitochondrial translation initiation pathway
Mitochondrial translation termination pathway
Mitochondrial translation elongation pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q9CXW2
TrEMBL
UniProt Splice Variant
Entrez Gene 64655
UniGene Mm.399511
RefSeq NM_025485
OMIM
CCDS CCDS23427
HPRD
IMGT
MGI ID MGI:1928137
MGI Symbol Mrps22
EMBL AK003836 AK013925 AK154600 BC021882 BC051198
GenPept AAH21882 AAH51198 BAB23027 BAB29061 BAE32703
RNA Seq Atlas 64655