Version 5.4
Mus musculus Gene: Larp7
Summary
InnateDB Gene IDBG-192978.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Larp7
Gene Name La ribonucleoprotein domain family, member 7
Synonyms C330027G06Rik; D3Wsu161e
Species Mus musculus
Ensembl Gene ENSMUSG00000027968
Encoded Proteins
IDBP-192980
La ribonucleoprotein domain family, member 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000174720:
This gene encodes a protein which is found in the 7SK snRNP (small nuclear ribonucleoprotein). This snRNP complex inhibits a cyclin-dependent kinase, positive transcription elongation factor b, which is required for paused RNA polymerase II at a promoter to begin transcription elongation. A pseudogene of this gene is located on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:127536954-127553348
Strand Reverse strand
Band G2
Transcripts
ENSMUST00000029588 ENSMUSP00000029588
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 2 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 18 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006396 RNA processing
GO:0035562 negative regulation of chromatin binding
GO:0036093 germ cell proliferation
GO:1900087 positive regulation of G1/S transition of mitotic cell cycle
Cellular Component
GO:0005654 nucleoplasm
GO:0030529 ribonucleoprotein complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000174720
View Gene Order
ENSBTAG00000009632
Not yet available
Cross-References
SwissProt Q05CL8
TrEMBL A3KML4
UniProt Splice Variant
Entrez Gene 28036
UniGene Mm.291032
RefSeq NM_138593
OMIM
CCDS CCDS38626
HPRD
IMGT
MGI ID MGI:107634
MGI Symbol Larp7
EMBL AC113952 AK012726 AK012772 AK015041 AK162147 BC020127 BC023165 BC029178 BC132266 BC132268
GenPept AAH23165 AAH29178 AAI32267 AAI32269 BAB28435 BAB28459 BAB29687 BAE36753
RNA Seq Atlas 28036

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca